Intrathecal drug pump is designed to deliver medication directly into the cerebrospinal fluid, targeting the intrathecal space around the spinal cord. This method provides a controlled release of pain ...

A progressive disease such as multiple sclerosis might be better managed using an intervention that can escalate as the disease advances, such as an intrathecal baclofen pump. The areas of the ...

Novartis (NYSE:NVS) said a Phase 3 study of an intrathecal formulation of its gene therapy Zolgensma, also known as OAV101 IT, met its primary endpoint in the treatment of children with spinal ...

Novartis said it plans to share the Steer results with regulators, including the FDA, to seek approvals for OAV-101 IT. Grant said a submission is expected in the first half of 2025. Novartis had ...

Objectives: To analyse the cerebrospinal fluid (CSF) values of the proinflammatory cytokines, interleukin 1β (IL1β), tumour necrosis factor α (TNFα), GM-CSF, of the anti-inflammatory cytokine TGFβ, of ...

By investigating patients with intrathecal delivery for a minimum of 12 months ... Patients had reported a stable level of analgesia with the pump, based on their attendance for pump refills at which ...

The Phase III STEER study met its primary endpoint showing an increase from baseline in HFMSE total score in patients with SMA treated with intrathecal onasemnogene abeparvovec (OAV101 IT) OAV101 IT ...

This has resulted in a resurgence of the use of lumbar intrathecal phenol injection (IP). The aim of this study was to investigate the authors' experience with IP. Methods: This observational study ...

For columnist Be, MS treatments are a way to ease his symptoms and make his life more comfortable until a cure is found.

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

Children with cerebral palsy (CP) face many challenges including impaired motor control and coordination, functional impairment, sensory disturbances, and, sometimes, communication difficulties ...

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