First-in-Human Study Provides Evidence that Sana’s Hypoimmune (HIP) Technology Enables Transplanted Islet Cells to Avoid Immune Rejection ... of Consistent Levels of Circulating C-Peptide, a Marker of ...

PDX-1 is a critically important transcription factor for the insulin promoter, is absent in glucotoxic islets, and, when transfected into glucotoxic ß-cells ... of elevated markers of oxidative ...

Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been ... reduction of haemoglobin A1c levels – a marker of blood glucose control – to 7% or ...

The following is a summary of “Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated ...

Current treatments for T1D, including islet cell transplants ... For Tregs, this means designing CARs that bind only to unique markers on transplanted tissues, ensuring precise immune protection.