One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

Glaucoma, the second leading cause of blindness globally, affects millions and is projected to reach 111.8 million cases by ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

[1] It is now accepted that serum calcium binds to the extracellular portion of the calcium-sensing receptor and activates a cascade of intracellular ... protein kinase C and phosphoinositides ...

Polo-like kinase 1 (PLK1) protects against genome instability by ensuring timely and accurate mitotic cell division. Here, the authors show that human PLK1 activity is sustained by the DNA damage ...

(Most of these details come from Fred Beckey’s seminal “Cascade Alpine Guide: Climbing and High Routes, Vol. 2: Stevens Pass to Rainy Pass,” one of the Bibles of the climbing set. Full of ...

An estimated 1 in 8,000 individuals, or 870,000 people worldwide, are affected by Facioscapulohumeral muscular dystrophy ...