2005; Kloss et al., 2007). NK cells and target cells were co-cultured for 4 h at 1:1 up to 10:1 effector:target ratios. Absolute cell counts were calculated using Flow-Count™ fluorospheres as internal ...

Gilead Sciences' cell therapy Kite Pharma has bulked up its position in natural killer (NK) cell therapies, pledging up to $2.3 billion for a partnership with Shoreline Bioscience focusing on off ...

4Research Unit of NK Cell Study, Chinese Academy of Medical Sciences, Beijing, China. Search for other works by this author on: 1Biomedical Sciences and Health Laboratory of Anhui Province, Division ...

All 13 cytokines/chemokines that were expressed by both PB-NK and PB-CAR-NK cells (IFNγ, GM-CSF, TNFα, IP-10, MIG, MCP-1, MCP-2, MCP-3, IL-13, GROα, MDC, MIP-1α, MIP-1β) were expressed at least ...

In laboratory experiments, doctoral students Tobias Bexte and Nawid Albinger succeeded in completely switching off an important immune checkpoint in NK cells that were specifically directed ...

The integration of clinical data and single-cell analyses highlights NK cell exhaustion as a key factor, offering insights with potential therapeutic implications. The work will be of interest to ...

Copyright: © 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...