Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Correspondence to: Dr Roberts, Department of Haematology, Hammersmith Campus, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; irene.roberts{at}ic.ac.uk Neonatal thrombocytopenia is a common ...

Thrombocytopenia typically occurs 1 to 2 weeks after administration. In rare cases, obinutuzumab can induce severe acute thrombocytopenia within days of infusion, a condition known as ...

Ongoing commercial launch of AUCATZYL® on track, with 24 treatment centers fully authorized as of January 10th- National Comprehensive Cancer ...

Detailed data from the Phase 1 first-in-human study of BRB-002 will be presented at the American College of Cardiology Scientific Session in March 2025. A Phase 2 proof-of-concept trial of BRB-002 in ...

Researchers suggest that the administration of intravenous immunoglobulin (IVIG) may not be necessary in women with low-risk FNAIT pregnancies. Fetal and neonatal alloimmune thrombocytopenia (FNAIT), ...

Clinically, patients with the disease may have a relatively benign course, with mild purpura secondary to thrombocytopenia, or may have progressive hepatic cirrhosis, hepatic failure and death.

Children with fetal and neonatal alloimmune thrombocytopenia (FNAIT) may be at increased risk of autism spectrum disorder, according to a recent study. The findings were presented at the 2024 American ...

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2014) and downregulating the MAPK pathway in macrophages (Wang et al., 2016). Furthermore, miR-223 is highly expressed in platelets (Plé et al., 2012), which explains why its abnormal expression can ...