Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

New Research in Fatty Liver Disease Aims to Help With Early ... Identifying a New Liver Defender: The Role of Resident Macrophages Apr. 25, 2024 — Researchers discovered liver resident ...

This study examined adipose and muscle inflammatory markers after treatment of humans with FOs and measured the effects of ω-3 fatty acids on adipocytes and macrophages in vitro. Insulin ...

Based on the association of CVD, diabetes and metabolic syndrome with the development and progression of NAFLD, the management of NAFLD should include aggressive management of cardiovascular risk ...

From mild to severe, the different types can help predict the risk of NAFLD progression to cirrhosis and liver cancer.

Background/aim: The purpose of this study was to examine the hepatic bacterial composition and metabolome characteristics of patients with NAFLD using 16S rDNA sequencing and metabolomics. The results ...

increased inflammatory responses and macrophage infiltration of the visceral adipose tissue, dyslipidaemia and fatty liver disease) even under standard dietary conditions and in the absence of ...

Many foods and ingredients in your daily diet, such as sugary baked goods, fast food, soda, and artificial sweeteners, may be ...

Our findings contribute to a better understanding of the mechanisms linking cellular senescence and fatty liver disease and support the development of new therapies targeting senescent cells for the ...

Obesity, non-alcoholic fatty liver disease, metabolic syndrome ... islet inflammation by preventing cytokine overproduction and macrophage infiltration; in addition, nuclear factor kappa B ...

We examined both LXR isoforms using LXRα-, LXRβ- and LXR-α/β-double-knockout mice. Finally, we investigated the effects of LXRs on fibroblasts and macrophages to establish the antifibrotic mode of ...