IN the nucleic acids, cytosine is connected to a sugar residue through N 1 of the pyrimidine ring. Here we describe the results of an X-ray diffraction analysis of crystals of N 1-methyl cytosine.

Tyr 34 also accepts a hydrogen bond from the 4-amino group of one of the methylated cytosine residues, further contributing to sequence selectivity. The crucial nature of the contacts between ...

Cytosine can undergo chemical modifications that play crucial roles in gene regulation and epigenetics. The most common modification is the addition of a methyl group to carbon 5, forming ...

This 1:1 ratio of A:T and G:C is crucial for maintaining the structure and stability of DNA. 5-Methylcytosine is a modified nucleobase formed by the enzymatic addition of a methyl group to the 5th ...