It seems that concentration gradients of morphogens outside a cell ... cascade—the first step of which is the cell "seeing" the morphogen by binding to it on the surface, and the final step ...
Morphogens are produced at specific locations in growing organs and spread through tissues, forming gradients of concentration. Depending on the morphogen concentration, cells take on different ...
The organizer cells were engineered to express the morphogen Wingless-related integration site 3A (WNT3A) and its antagonist Dickkopf-1 (DKK1) in different gradients. This allowed the researchers ...