Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent ...

South San Francisco biotech Pionyr was sold two years ago. Now three of its leaders want to test a trio of drugs beyond ...

In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of ...

MSK experts believe that giving the targeted drug asciminib to patients with chronic myeloid leukemia at the beginning of ...

在全球范围内，急性髓系白血病（Acute Myeloid Leukemia，AML）被视为一种极其复杂且具有高度异质性的血液恶性肿瘤。其治疗难度颇大，且预后多数不佳。患者即便经历过多种现代治疗手段，包括化疗、放疗及异基因造血干细胞移植（ allo-HSCT），仍然有相当高的复发率。这种情况对患者及其家庭造成了巨大的心理和生理压力，非常迫切地需要新的治疗方法来改善患者的生存状况。 2025年1月14 ...

Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of ...

Medically reviewed by Doru Paul, MD Leukemia is a cancer of the blood-forming tissues that often develops in the bone marrow.

The study demonstrated a poor prognosis overall for patients with acute myeloid leukemia (AML) who were previously treated ...

Dong adds that further research might also shine a light on the origins of some neurodevelopmental disorders. Other genes from the ASXL family can be mutated in neural stem cells, which may lead to ...

Novel CD37 antibody-drug conjugate shows promise in targeting the Achilles’ heel of acute myeloid leukemia cells.