Natriuretic peptides, especially B-type natriuretic peptide (BNP), have primarily been regarded as biomarkers in heart failure (HF). However, they are also possible therapeutic agents due to their ...

Circulating concentrations of B-type natriuretic peptide (BNP) and the N-terminal fragment (NT) of its prohormone (proBNP) are related to cardiac function and have emerged as clinically useful ...

Methods 67 patients with their first anterior AMI (median age, 64 years; male, 76%) underwent prospective evaluation of plasma concentrations of the molecular forms of A-type and B-type natriuretic ...

Objective: To determine normal values of plasma B type natriuretic peptide from infancy to adolescence using a commercially available rapid assay. Setting: Tertiary referral centre. Design: The study ...

However, anaemia sometimes remains undetected because the superficial cardiac function does not precisely reflect the adverse impact of anaemia. Plasma B-type natriuretic peptide (BNP) could be ...

Such patients may be less responsive to positive inotropic agents, whereas the beneficial effects of nesiritide, which are not dependent on the β-adrenergic receptor signal-transduction pathway ...

The company has suggested that vosoritide’s mechanism of action, a CNP analogue that binds to natriuretic peptide receptor B (NPR-B), addresses a “master regulator” of bone growth and could ...

The receptor for IL-33 ... The PRIDE study (or Pro-Brain Natriuretic Peptide Investigation of Dyspnea in the Emergency Department), a prospective, blinded study of patients presenting to an ...

Medications such as angiotensin receptor blockers (ARBs) and ARNIs have demonstrated the ability to significantly attenuate NEP activity (Dahrouj et al., 2013). Inhibiting retinal NEP activity and ...

Data from 809 patients in the PARAGON‐HF (Prospective Comparison of Angiotensin Receptor–Neprilysin Inhibitor With Angiotensin‐Receptor ... greater left ventricle wall thickness, higher N‐terminal pro ...

The top 5 proteins with the largest absolute coefficients in the IS protein risk score, including GDF15 (growth/differentiation factor 15), PLAUR (urokinase plasminogen activator surface receptor), NT ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Once candidate monobodies, based on binding affinity to either ...