EurekAlert!1y
Overview of the mechanisms of action for new and future therapies in the management of inflammatory bowel disease. (IMAGE)
Antitumour necrosis factor alpha (anti-TNFα) agents include infliximab, adalimumab, golimumab, AVX-470 and OPRX-106. Janus kinase (JAK) inhibitors: tofacitinib, filgotinib and upadacitinib.
Medscape9d
Warfarin-Induced Skin Necrosis
[31] This may be a mechanism whereby antiphospholipid antibodies ... of dermal venules and veins and may contribute to tissue necrosis. Our patient was simultaneously treated with ...
Nature2d
Rash induced by anti-tumor necrosis factor agents in an adolescent with Crohn's disease
Background. A 17-year-old white male with Crohn's disease who was receiving maintenance infusions of the anti-tumor necrosis factor (TNF) agent, infliximab, presented with a new-onset psoriasiform ...
Medscape25d
Time to Dispense with the Clock and Move to Tissue-based Decision Making?
Necrosis is a form of traumatic cell death ... However in the penumbra, there are multiple cell death mechanisms that are activated: excitotoxicity and ionic imbalance, oxidative stress, and ...
Nature1y
From IFN to TNF: a journey into realms of lore
A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J. Cell Biol. 116 , 545 ...