Bits of DNA from mitochondria can skip surprisingly fast into our genome and may reduce lifespan M ost of us remember two ...
New research identifies E-TCmito as a key link between neuronal activity and mitochondrial function, highlighting its ...
Mitochondrial dysfunction in the brain can disrupt the balance of calcium ions inside and outside neurons, making them fire more readily than they should. Kubota-Sakashita had previously found ...
In some specialized cell types, like neurons and sperm, energy needs are high and mitochondria are trafficked long distances, dictating unique needs for the shape of the mitochondrial network.
Notably, this coupling crumbles with age in mice. Restoring it not only bolstered neuronal energy reserves, but also strengthened synaptic signaling and counteracted memory loss in old animals.
"Additionally, we created a new research model based on mouse neurons that significantly advances the study of protein import into mitochondria in brain cells. We believe that our findings ...
Scientists at the University of Copenhagen have uncovered a breakthrough in understanding Parkinson’s disease (PD), a ...
They focused on the presence of mitochondria in axons, the long tendril-like appendages that stretch out of neurons and form the necessary connections that allow signals to be transmitted inside ...
"Work is already under way to identify existing licensed drugs that can boost the mitochondria and repair the motor neurons. This will then pave the way to test them in clinical trials." ...
Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...
Recent studies have identified the significance of mitophagy, a quality control process that removes dysfunctional ...