Ferroptosis was determined by MDA levels, SOD levels, mitochondrial iron accumulation and ROS production. Ferroptosis-related proteins Slc7a11, Nrf2 and Gpx4 levels were measured by western blot, ...

Ferroptosis is a programmed cell death caused by iron‐dependent accumulation and cellular lipid peroxides, which is different from apoptosis and pyroptosis. This study investigated the possible effect ...

Growing evidence indicates that inducing ferroptosis through various mechanisms, particularly by inhibiting System Xc-, depleting glutathione (GSH), and inactivating glutathione peroxidase 4 (GPX4), ...

In this manuscript, the authors consider the effects of eugenol (EUG), a plant-produced substance known to reduce oxidative stress in various cellular contexts via Nrf2, in alleviating the effects of ...

Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...

Department of Gastroenterology, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing ...

Supervised clustering provides better resolution in cell cluster screening than is achieved by traditional unsupervised clustering. The effects of 17α-estradiol on metabolism, stress responses, ...