Four non-nucleoside RT inhibitors (NNRTIs ... ide analog reverse-transcriptase inhibitor monophosphate (red) is removed from the end of terminated DNA (bottom). The most likely pyrophosphate ...

Acute kidney injury (AKI) can occur following tenofovir-induced tubule dysfunction or as a result of severe mitochondrial dysfunction and lactic acidosis induced by nucleoside reverse ...

Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León 64460, México Megan Centre of Applied Mycology (MCAM), Faculty of Engineering and Applied Sciences, Cranfield University ...

Professor Sunhee Choi joined the chemistry faculty at Middlebury College in 1987. She earned her B.S. in Chemistry at Seoul National University and Ph.D. in Physical Chemistry at Princeton University.

The origins of immunotherapy go back to early centuries of history as illustrated by the fight against smallpox. Realization that survivors were immune to the disease eventually led to the practice of ...

Department of Anesthesiology, Zhongnan Hospital of Wuhan University, TaiKang Center for Life and Medical Sciences, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China Key ...

Cyclic guanosine monophosphate-adenylate synthetase (cGAS) is a cellular DNA sensor that primarily recognizes double-stranded DNA, i.e., mtDNA, using ATP and GTP as substrates to produce the second ...