In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used ...

Mutational signatures etched into the cells' genome by an anti-cancer drug called temozolomide (TMZ) uncover an Achilles' heel for TMZ chemotherapy resistance, according to new research.

Peter Mac scientists have found a way to use the powerful gene editing tool CRISPR to silence cancer-causing gene mutations ...

The drug candidate acts by targeting CTP synthase 1 (cytidine triphosphate synthase). Step Pharma is a pharmaceutical company that discovers and develops novel therapeutics for the treatment of cancer ...

The antisense oligonucleotides market is set to grow at a 6.6% CAGR, reaching $5.5 billion by 2033. Expanding applications in ...

An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.

A 10-panel drug test is a common way to check for various drugs in a person’s body. It typically involves testing urine for drugs, such as cannabinoids, opioids, and more. Typically, traces of ...

Australian researchers have found a way to silence cancer-causing gene mutations In a new study researchers from Melbourne Peter MacCallum Cancer Ce ...

Chemical probes with defined targets can be attractive as drugs in clinical pharmacology. Base editors chemically convert one nucleotide base to another. The development of the first base editor ...

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

William Thilly had many job titles during his life: leader of groundbreaking research into human genetic mutations, ...