从狩猎伙伴到家庭成员，狗的温顺、忠诚和善解人意，使它们赢得无数“铲屎官”的心。然而，近年来，随着一系列恶犬伤人事件的频繁发生，这一和谐景象背后隐藏的健康风险也逐渐浮出水面，引起了社会各界的广泛关注和深入讨论。对狂犬病毒的研究与防控，也成为了公共卫生领 ...

The two pumps commonly found to confer chemoresistance in cancer are P-glycoprotein and the so-called multidrug resistance–associated protein (MRP). Because of their function and importance ...

For example, another withdrawn drug, mibefradil, which in combination with simvastatin caused several cases of rhabdomyolysis 4, is an inhibitor of transporters such as P-glycoprotein, as well as ...

In many of these failures, the guilty agent is a protein called P-glycoprotein. Like a misguided housekeeper, this protein sweeps drugs out of diseased cells. In 2004, a team of scientists at ...

The company also announced new real-world evidence showing statistically significant and sustained HAE attack rate reductions after initiating ORLADEYO in patients with HAE, regardless of their ...

These pumps are called P-glycoprotein mediated pumps and are named for the type of protein used to construct and operate them. Though all cells have the ability to develop such a pump, normal cells ...

The ritonavir in Paxlovid blocks some critical pathways that metabolize (break down) drugs. Specifically, Paxlovid blocks both the liver enzyme cytochrome P450 3A4 and p-glycoprotein. This results in ...

Learn about the p sound with the wizards! close Sorry, something went wrongCheck your connection, refresh the page and try again. Pick the item that uses the correct ...

Rhodiola (Rhodiola rosea) is an herb containing salidroside, an active ingredient that may improve depression, reduce stress, fight stress-related fatigue, and boost exercise performance. Salidroside ...

They both have a major surface glycoprotein HA that are responsible for binding to cell-surface receptors and for entering into host cells for replication. We are investigating the structures and ...

Sean Combs - also known as P Diddy and Puff Daddy - will go on trial on sex trafficking charges in May next year. The rapper has been repeatedly refused bail after pleading not guilty to three ...