In many of these failures, the guilty agent is a protein called P-glycoprotein. Like a misguided housekeeper, this protein sweeps drugs out of diseased cells. In 2004, a team of scientists at ...

The company also announced new real-world evidence showing statistically significant and sustained HAE attack rate reductions after initiating ORLADEYO in patients with HAE, regardless of their ...

The two pumps commonly found to confer chemoresistance in cancer are P-glycoprotein and the so-called multidrug resistance–associated protein (MRP). Because of their function and importance ...

These pumps are called P-glycoprotein mediated pumps and are named for the type of protein used to construct and operate them. Though all cells have the ability to develop such a pump, normal cells ...

Specifically, Paxlovid blocks both the liver enzyme cytochrome P450 3A4 and p-glycoprotein. This results in increased levels of medications metabolized by these pathways in the body and a higher risk ...

Rhodiola (Rhodiola rosea) is an herb containing salidroside, an active ingredient that may improve depression, reduce stress, fight stress-related fatigue, and boost exercise performance. Salidroside ...

Try to show that a connection exists, using real data going back to 1948. For your results to be publishable in an academic journal, you’ll need to prove that they are “statistically significant” by ...

Early treatment of the first MOGAD acute attack may prevent future relapses and reduce long-term humoral autoimmunity in patients.

从狩猎伙伴到家庭成员，狗的温顺、忠诚和善解人意，使它们赢得无数“铲屎官”的心。然而，近年来，随着一系列恶犬伤人事件的频繁发生，这一和谐景象背后隐藏的健康风险也逐渐浮出水面，引起了社会各界的广泛关注和深入讨论。对狂犬病毒的研究与防控，也成为了公共卫生领 ...

Donald Trump says he would use the power of the presidency to order F.B.I. investigations and criminal prosecutions of his political foes. He was largely thwarted in this in his first term. But ...

Clesrovimab led to significant reductions in RSV-associated MALRI, hospitalizations, and was comparable in safety to palivizumab.

Positive data from 876-patient head-to-head trial versus Shingrix® shows amezosvatein elicits robust humoral and cellular immune responses ...