suggesting that the modified protein is not being routed for rapid degradation through this pathway. However they did observe that another protein, the ubiquitin binding protein p62, was also ...

The cGAS-STING signaling pathway is a critical component of the innate immune response, playing a significant role in various diseases. As a central element of this pathway, STING responds to both ...

Creation of all things; creation of Adam and Eve; temptation by Satan; Adam and Eve rebel against God and forfeit Garden of Eden. On that day, Adam and Eve, the father and mother of all mankind, chose ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

The NFL has announced its International Player Pathway (IPP) program Class of 2025 featuring 14 athletes representing 13 nations around the world, as the league continues to focus on creating more ...

Host defense against pathogens is essential to restrict infectious diseases, and understanding the underlying biology is paramount to the development of new treatment strategies. This exciting ...

The implication of autophagy in two major pathogenic pathways in SLE suggests the potential to use inhibition of autophagy ... UK), or Fixable Viability Dye (eBioscience, UK). Intracellular staining ...

Additionally, targeting the Laforin-Mst1/2 complex to inhibit the Hippo signalling pathway may impede liver tumour initiation. Although technologies like PROTAC are addressing the challenge of ...

The NFL has announced its International Player Pathway (IPP) program Class of 2025 featuring 14 athletes representing 13 nations around the world, as the league continues to focus on creating more ...