Primary sclerosing cholangitis (PSC) is a rare and chronic disease of the liver that causes inflammation and narrowing of the ...

PSC is closely linked with autoimmune colitis like ulcerative colitis or Crohn’s ... Antibiotics are required often if there is fever and patients may need endoscopic retrograde cholangiography (ERCP) ...

Although the use of UDCA has shown some promising effects on liver biochemistries in patients with PSC, its overall impact on disease progression (assessed by ERCP or liver histology), symptoms ...