COT, cross-over trial; RCT, randomized controlled trial.

The gastrointestinal prokinetic agent stimulates muscle contractions in the colon, increasing bowel movement. The approval of prucalopride was supported by data from 6 randomized, double-blind, ...

These therapies include currently available prokinetic drugs, novel medical therapies, and the promising technique of gastric electrical stimulation. In one large series, about a third of patients ...