The modelling is believed to be the first of its kind to couple gastric biomechanics with pill movement and drug dissolution to quantify an active pharmaceutical ingredient passing through the pylorus ...
Meanwhile those around the sphincter-like pylorus intermittently dilate to allow the passage of food into the small intestine ...
Clin Drug Invest. 2005;25(7):435-443. Drug absorption and, therefore, the clinical effects of orally administered drugs strongly depend on their mode of transit through the gastrointestinal tract ...
Thankfully, there is a growing body of evidence to guide determination of the distance a tube is to be inserted. In current practice, distance is externally measured to predict the internal ...