In this review, we summarise what is currently known about the potential function of primary cilia in the pathogenesis of this disease. As primary cilia represent a key cellular structure for signal ...

Indiana University School of Medicine researchers have uncovered compelling evidence that children with primary ciliary dyskinesia (PCD), a rare genetic disorder affecting airway function ...

There are several types of kidney (renal) cancer. Each type is potentially curable if it’s found and treated early before the cancer has a chance to spread. Kidney cancer is categorized in stages from ...

This could be an ideal model to study not just the role of IFT in connection with ciliary function but also ciliopathies. Further, from an evolutionary perspective, it is fascinating to compare IFT ...

Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement for canonical Wnt/β-catenin signaling in Hh-driven BCC ...

In chronic kidney disease, the kidneys are unable to filter excess water and waste out of your blood as they should. Early detection of kidney disease combined with dietary and lifestyle changes can ...

All the cilia were visualized with anti-acetyleated tubulin. The photoreceptor double cones were stained with zpr-1 antibody in panel H, and nuclei were stained with DAPI in panel I. Immunostaining ...

Primary membranous nephropathy is a type of kidney disease that affects the natural filtration process, resulting in excess protein output. When left untreated, kidney failure may develop.

Potassium is a mineral needed for vital bodily functions. But people with kidney disease may need to know which high potassium foods to avoid. Here we discuss how to create such a diet.

Demographic data, tumor type, treatment, visual outcomes, and mortality data were recorded. Results: 26 patients (33 eyes) with choroidal/ciliary body metastasis were identified. Primary malignancies ...