Signaling via phosphorylation-regulated protein-protein interactions often involves flexible or unstructured proteins. Detailed biophysical and computational studies on one such interaction reveal ...

CXCL13, a signaling protein that is produced immediately after infection with B. burgdorferi and triggers an immune response, could provide a more accurate diagnosis—if it were known at what ...

New Activin R-based medications can emerge as perfect solutions for balancing weight loss and muscle building, making a ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

Positively associated proteins were enriched in pathways like tyrosine kinase signaling, linked to cellular stress, while negatively associated proteins related to neuron projection regeneration ...

Scientists at St. Jude Children’s Research Hospital have uncovered the intricate circuit cues behind neuronal cell maturation ...

Scientists have uncovered how developing neurons migrate from the germinal zone, a process critical for proper brain circuit ...

Ram Savan explained that some proteins in the body act as sentinels. When they detect the presence of RNA viruses, they activate interferons through the mitochondrial antiviral signaling (MAVS ...

A new study showed that SOCS1 regulation of GM-CSF signaling is dose-dependent. The study, which involved generating a novel ...

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...