Gastrulation is a crucial stage in embryonic development, during which extensive cell migration causes a single cell layer ... the midline of the developing embryo, the primitive streak.
We use mammalian embryo, embryo-derived stem cell, and organoid models, as experimentally tractable platforms for our studies. We have a history of applying cutting-edge high-resolution quantitative ...
To demonstrate this capability, we chose single human cells from eight-cell-stage embryos, collected and analyzed for expression of 46 developmental genes. One of the hottest trends today in life ...
Each one of us starts off as a single cell when an egg and a ... The cells on the inside layer of this very early embryo can make all of the cell types needed in your body. They're called stem ...
Most importantly, zebrafish are the fastest developing vertebrate model system, going from a one-cell embryo to an embryo with a functioning nervous system in less than 24 hours. Additionally, ...
The invariant lineage promises single-cell resolution to worm biology, as one can reliably identify any cell at ... we found that the pace/length of cell cycle is under tight control by fate ...
By taking a gene from single-celled lifeforms and introducing it into mouse cells, researchers generated stem cells, which, when injected into a developing embryo, helped give rise to a living ...