To test this theory, they studied a type of skin cell called fibroblasts. Fibroblasts rush to a fresh wound and jump-start the healing process. In the study, twice as many fibroblasts fled to ...
Acting as a vital protective barrier, the skin shields an organism's internal tissues and organs from damage. As a result, an organism must quickly repair the barrier after a skin injury occurs. To ...
The results are relevant for the development of novel skin cancer therapies, particularly in the field of immunotherapy. The study was recently published in the journal “Nature Communications”.
Upon wounding healthy skin, inflammatory cells combat infection, fibroblasts migrate into the wound bed and contract the defect, and finally re-epithelialisation closes the gap. However, these ...
After tissue repair, wound bed fibroblasts re-establish a quiescent state to maintain skin homeostasis. Deregulation of these complex developmental processes in the dermis is associated with several ...
This discovery holds significant promise for the development of wound healing ... microscopy, fibroblast differentiation is most active when the elastin content of the skin extracellular matrix ...