This important study reveals a critical role of the transcription factor NR2F2 in mouse fetal Leydig cell (FLC) differentiation. With elegantly carried out experiments, the authors provide compelling ...

Adrenal steroidogenesis inhibitors such as metyrapone and osilodrostat are drugs that reliably suppress cortisol among medical treatments for this syndrome (4, 6–8). Metyrapone exhibits a short ...