During immune synapse formation, the microtubule organizing centre (MTOC) and the Golgi of the T cell reorient towards the APC to ensure targeted delivery of signalling molecules, such as the T ...

However, we found no functional defects in BCR signalling, immunological synapse formation, or processing and presentation of the internalized ... 10 mm HEPES and 100 U/ml penicillin/streptomycin].

CAR T cell therapy revolutionizes oncology by using engineered T cells to target and eliminate cancer cells, improving ...

This study is an open-label, dose-escalation/expansion Phase I clinical trial (NCT05920876), aiming to assess the safety of ...

Your immune cells are what they eat Scientists establish novel link between cell nutrition and identity, say targeting nutrient-dependent activity could improve immunotherapies Date: December 12 ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

Seoul National University Bundang Hospital announced on the 3rd that Lee Pyeong-bok, head of the Pain Center (professor of ...

Chimeric antigen receptor (CAR)-T cells and T-cell therapies have been used in the treatment of various cancers for several years. In a review published in JAMA, a research team led by Christian ...

Background: Clinical studies have demonstrated the high efficacy of using chimeric antigen receptor (CAR)-T cells targeting B-cell maturation antigen (BCMA) and orphan G protein-coupled receptor, ...

Razer Synapse may occasionally refuse to launch due to compatibility issues with Windows ... By following the methods below, you can address these issues and help ensure that they don’t interfere with ...

New research uncovers a key cellular mechanism driving Alzheimer's disease, offering potential insights for future treatments ...