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【企业资讯】Mesoblast的启示:中国干细胞企业能否迎风而上?
MSC通过TNF-α介导活化NF-kB而发挥免疫抑制作用,并通过siRNA干扰技术验证了降低或敲除TNFR1会降低MSC的淋巴细胞抑制能力,不同表达水平的TNFR1与细胞的淋巴细胞抑制能力成一定的相关性。因此,Mesoblast将TNFR1作为Remestemcel生物功能的放行指标,并且在临床试验中 ...
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