Two anti-transferrin receptor (TfR) nanobodies, V H H123 specific for mouse TfR and V H H188 specific for human TfR (huTfR) were used to track transplants non-invasively by PET/CT in mouse models, ...

Background Heart failure (HF) guidelines recommend routine testing for iron deficiency (ID) and, for those with ID, ...

Transferrin receptor 2 (TfR2) is a key molecule involved in the regulation of iron homeostasis. Mutations in humans cause type 3 haemochromatosis and a targeted mutation in mice leads to iron overload ...

Oxidative stress induces both insulin resistance [by decreasing internalization of insulin [51]] and increased ferritin synthesis. The fraction of nonused and highly toxic iron is stored as ...

And this is because transferrin needs the previously mentioned “ticket”, which is a unique receptor for input, the number of which is limited on the cell surface. The research of scientists ...

The complement C3a/C3aR pathway is associated with treatment resistance to gemcitabine-based neoadjuvant therapy in pancreatic cancer. Read the article here: https://lnkd.in/gvya9DtP ...

And this is because transferrin needs the previously mentioned "ticket", which is a unique receptor for input, the number of which is limited on the cell surface. The research of scientists from ...

Background: Pharmacotherapy for restless legs syndrome (RLS) may be ineffective or complicated by side effects. Uncontrolled series using pneumatic compression devices (PCDs) have been shown to ...

Serum ferritin is the most powerful test for iron deficiency (A). Upper and lower GI investigations should be considered in all postmenopausal female and all male patients where IDA has been confirmed ...

A 14-year-old patient presented to the ED with a 12-month history of joint pains and a 2-month history of headaches and ...