Chromosomal abnormalities can include two basic categories: numerical or structural. A structural abnormality can include an alteration to the structure of the chromosome, as the name suggests.
Two separate hybridization mixtures were prepared ... Before hybridization, metaphase chromosomes on slides were treated with 100 μg/ml RNase for 1 h at 37 °C and 30 μg/ml pepsin (in 0.01 ...
In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...