Research on tumor metabolism not only helps us to better understand tumor biology but also provides ... it can synergistically suppress the proliferation of drug-resistant lung adenocarcinoma cells ...

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

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These epigenetic modifications, in turn, are regulated by physiology and metabolism. Steroid hormone estrogen and metabolites such as S-adenosyl methionine and acetyl CoA directly impact DNA and ...

aDepartments of Medicine (Division of Endocrinology and Metabolism) and Biochemistry and Molecular Biology ... Note that the oxidative fate of pyruvate is to be irreversibly decarboxylated to acetyl ...

HIF1α identified as key regulator that induces cancer-killing ability of hypoxic T cells, playing a role in ICB resistance.

Losing weight is a goal that many people often feel is impossible to achieve. Dieting demands strict guidelines, and workouts ...

Pyruvate and acetyl-CoA, the key metabolites involved in citramalate ... how their approach can be adapted to optimize other metabolic pathways in cyanobacteria, with the aim of expanding the ...

This is because pyruvate and acetyl-CoA are also used to create many other ... how their optimization approach could be used for other metabolic pathways within cyanobacteria.

Inherited metabolic diseases (IMDs) pose a particular challenge to diagnosis ... Fat oxidation is the mechanism whereby the body metabolises fat for the production of energy either by utilisation of ...