OCT4 and c-MYC are widely accepted as CSC markers. In this study, we examined the immunohistochemical co-expression of c-MYC and OCT4 with Ki-67 in colorectal cancers (CRC) and the relationship ...

MYC on the path to cancer. Cell 2012; 149: 22-35. 17. O'Hagan RC, Ohh M, David G, et al. Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression. Genes Dev ...

资料显示，上述斯坦福大学的研究本质源于日本科学家山中伸弥的iPS技术。2006年，山中伸弥将四种转录因子——Oct4、Sox2、Klf4和c-Myc（后被称作山中因子）导入小鼠皮肤细胞，成功将其诱导回干细胞状态，相当于把成年人变回婴儿。这一颠覆性突破令他荣获2012年 ...

该研究采用了多种转录因子组合，包括经典的OSKM因子（OCT4、SOX2、KLF4、MYC）和用于滋养干细胞（trophoblast stem cells）诱导的GETM因子（GATA3、EOMES、TFAP2C ...

The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the field of medicine ever since the ground-breaking discovery in 2006 that overexpression of four specific ...

David Sacks, a venture capitalist and Trump's new crypto & AI czar. © 2024 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of ...

C is a programming language designed by Dennis Ritchie at Bell Labs. C is very widely used, straightforward, and can be compiled to a number of platforms and operating systems. C is an imperative ...

Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan ...