产品活性： PF-07104091 hydrate 是一种高效选择性的 CDK2/cyclin E1 和 GSK3β 抑制剂，其 Ki 分别为 1.16 和 537.81 nM。PF-07104091 hydrate ...

Gut microbiota-derived phenylacetylglutamine accelerates aging by driving cellular senescence through mitochondrial ...

FDA grants Fast Track Designation for azenosertib in Cyclin E1 positive cancer. Clinical data update to follow on January 29, 2025. Zentalis Pharmaceuticals announced that the U.S. FDA has granted ...

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...

Zentalis Pharmaceuticals has won a U.S. Food and Drug Administration fast-track designation for its lead product candidate azenosertib for certain cancer patients with high levels of the Cyclin E1 ...

CT表现 腹腔内靠近脊柱左前方腹膜后区域见不规则团片状稍低密度影，范围约 26 × 28 mm，边界尚清，病灶内部区域密度大致均匀，偏后方区域脂肪间隙模糊（冠状位蓝色箭头） 增强检查病灶动脉期明确不均匀性强化，内见小片状、裂隙状稍低密度影 ...

Initial clinical data from Phase 1 SAD/MAD study of VAV1-directed molecular glue degrader (MGD) MRT-6160 expected in Q1 2025Additional clinical ...

All rights reserved. Registered office: The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP. A Charity, Not for Profit. Company Limited by Guarantee. Registered in England No.

Patients with HR+/HER2− metastatic breast cancer without previous systemic therapy were randomly assigned to receive either ...

Stock analysts at StockNews.com assumed coverage on shares of MEI Pharma (NASDAQ:MEIP – Get Free Report) in a research report issued to clients and investors on Friday. The firm set a “buy” rating on ...

Kronos Bio (NASDAQ:KRON – Get Free Report) and Aerovate Therapeutics (NASDAQ:AVTE – Get Free Report) are both small-cap medical companies, but which is the better investment? We will contrast the two ...

A research team has successfully utilized human respiratory organoids (mini-organs) to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation ...