In 'Bedside to Bench', Clare M. Lloyd and Sejal Saglani examine how recent human studies are putting the focus on the epithelium as a major contributor to asthma. The findings shift the emphasis ...
Cell death in the intestinal epithelium has to be tightly regulated and irregularities might cause pathologies. Excessive cell death has been associated with chronic inflammation as seen in patients ...
Design We generated 42 lines of human and murine organoids from gastric and intestinal segments of both adult and fetal tissues. Genome-wide RNA-seq of the organoids provides an expression atlas of ...
The repository contains: scripts to generate the paper figures a case study which complements the manuscript the code for the marker gene detection study from the supplementary material The main part ...
Cell competition in epithelial tissue eliminates transformed cells expressing activated oncoproteins to maintain epithelial homeostasis. Although the process is now understood to be of mechanochemical ...
Aim: To analyse clinical features of drusenoid pigment epithelium detachment (PED) in age related macular degeneration. Methods: 61 eyes of 32 patients with untreated drusenoid PED were followed for ...