Germline development is the development of the cell lineage that gives rise to the reproductive cells, called gametes, of sexually reproducing organisms. Primordial germ cells, the founder cells ...

Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural ...

Real-World Treatment Patterns After Discontinuation of Venetoclax or BTKis in the Frontline Setting Among Older Adults With Chronic Lymphocytic Leukemia Indications for and implications of germline ...

Largescale changes in the genome inherited from parents are significant risk factors for pediatric solid tumors, such as Ewing sarcoma, neuroblastoma ...

The previous study found 391 regions in the dog genomes that differed between the Chornobyl NPP and City populations — with ...

1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. 2Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. 3Clinical and ...

The foremost is: as the germline mutations account for only 12% of the breast cancer cases, which other factors (genetic and/or environmental) are involved in the observed high incidence of breast ...

An expert spoke with CURE® about the importance of information that can be gained from genetic testing for patients with breast cancer. Germline testing, or genetic testing of the DNA that a person ...

Results: Of the 197 new rhesus IGHV germline sequences identified, 116 (59%) were validated by at least two methods, and 143 (73%) were found in at least two macaques or two sample sources. About 20% ...

In support of this study and a broader transition to HiFi long-reads, PacBio and Radboudumc are accelerating efforts to study ...