Background: Cerebral small vessel disease is a common cause of vascular dementia. Both discrete lacunar infarcts and more diffuse ischaemic changes, seen as confluent high signal (leukoaraiosis) on T2 ...

Objective: To develop brief assessment tools that are better adapted to the neuropsychological profile of cerebral small vessel disease. Methods: 32 subjects with ischaemic leukoaraiosis (history of ...

Two main forms of sporadic SVD have been described: arteriolosclerosis and cerebral amyloid angiopathy (CAA). The former describes a group of small vessel pathological processes. Arteriolosclerosis ...

Introduction: Diagnostic classification systems and guidelines posit distinguishing patterns of impairment in Alzheimer’s (AD) and vascular dementia (VaD). In our study, we aim to identify which ...

About 25% of patients with acute ischemic stroke have lacunar infarct on follow‐up imaging. In this secondary analysis from the AcT (Alteplase Compared With Tenecteplase) trial, we assessed if there ...

The most effective treatment for carotid artery stenosis is carotid endarterectomy (CEA). To date, randomized trials of this procedure versus best medical care have excluded patients aged 80 years ...