2025年1月6日，海军军医大学/中国医学科学院基础医学研究所/南开大学曹雪涛团队合作在Cell Research在线发表题为“Nonenzymatic lysine D-lactylation induced by glyoxalase II ...

海军军医大学王品教授、曹雪涛院士、于益芝教授等在 Cell Research 期刊发表了题为： Nonenzymatic lysine D-lactylation induced by glyoxalase II substrate SLG ...

In diabetes, hyperglycemia drives nonenzymatic glycation and oxidation of proteins and lipids, enhancing irreversible formation of advanced glycation endproducts (AGEs); these processes are ...

【导读】免疫代谢在免疫和炎症的调节中至关重要；然而，预防异常激活诱导的免疫病理的机制在很大程度上仍不清楚。2025年1月6日，海军军医大学/中国医学科学院基础医学研究所/南开大学曹雪涛团队合作在Cell Research ...

Forty-five inbred male Lewis rats were randomly assigned to 3 experimental groups: group Gl included 15 non-diabetic control rats (NC), group GIT included 15 alloxan-induced diabetic rats (DC), and ...

Proton pump inhibitor therapy is well tolerated at standard doses; even a fivefold increase in the AUC of PPIs appears to cause only negligible side effects. The clinical relevance of these ...

1 Department of Immunology, Harvard Medical School, Boston, MA, United States 2 The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) and Harvard, ...

Genetic polymorphisms have been described in the case of several CYP isoenzymes. The best explored example of this phenomenon is the CYP2C19 polymorphism. In this table the most frequent alleles ...

1 Department of Orthopaedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China 2 Department of Orthopedics, People’s Hospital of Rizhao, Rizhao, Shandong, China ...

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Department of Chemical and Pharmaceutical Biology, Groningen Research Institute of Pharmacy, University of Groningen, Antonius Deusinglaan 1, Groningen 9713AV, The Netherlands ...