Furthermore, RNA-seq analyses of BCP-treated HepG2 cells identified 433 protein-coding DEGs. Integrative analyses revealed five BCP-targeted DEGs regulating the MAPK signaling pathway. Among these ...

oxLDL, oxidized low-density lipoprotein; ECs, Endothelial cells; VSMCs, vascular smooth muscle cells; TNF-α, Tumor necrosis factor-alpha; IL-1β, interleukin-1β; IL-6, Interleukin-6; MCP-1, monocyte ...

They result from germline mutations in genes encoding kinases and other proteins interacting in the RAS-MAPK pathway. This review summarises these disorders, discussing their presenting features and ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...