Purpose Pharmacokinetic considerations in patients who have undergone Roux-en-Y gastric bypass (RYGB) are explored. Summary The prevalence of obesity, especially morbid obesity, has dramatically ...

The optimization of pharmacokinetic properties is crucial in the design of successful drug candidates. Tune in as Punit Marathe shares the key pharmacokinetic concepts including clearance, volume of ...

A small study on the pharmacokinetic properties of ibuprofen and paracetamol, when taken concurrently, found no significant change in kinetic parameters of the two drugs. [6] Here we report the ...

Assessing the pharmacokinetics (PK) of antibody-drug conjugates (ADCs) in both preclinical and clinical settings is crucial for their development. Biotransformation processes can lead to the ...

However, pharmacokinetic (PK) data on melatonin in preterm infants is lacking. The aim was to examine the preterm pharmacokinetic profile. Methods: We conducted a multi centre, open label study in ...

Learning is reinforced via application of modelling and simulation skills to real pharmacokinetic and pharmacodynamic data. The course has been developed with an emphasis on mechanistic approaches to ...

today announced the initiation of a pharmacokinetic (PK) and tolerability study in partnership with its contract research organization (CRO), AmplifyBio. The study is designed to assess the ...

Priority will be given to students with the strongest grades from high-ranking institutions. We expect successful applicants to demonstrate: Interest and basic understanding of pharmacokinetics and ...