The drug candidate is administered by intravenous, infusion and intratumoral route as a solution. It is a single-stranded phosphorothioate antisense oligodeoxynucleotide (18-mer). It is also under ...

At 2 h before the glutamate pulse, 12.5 μM double-stranded phosphorothioate oligonucleotides were added, containing either the wild-type or the mutated NF-κB consensus binding motif used in the ...

In IP-RPLC, oligonucleotides are primarily eluted based on their lengths, and it is possible to separate modified oligonucleotides (such as phosphorothioate oligonucleotides, locked nucleic acids, ...

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Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K. Department of Chemistry, University College London, 20 Gordon Street, London WC1H ...

Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States ...