Other than having high blood pressure, I am healthy, eat a Mediterranean-style diet, and exercise most days. Since 2021, I have been taking one tab of amlodipine/valsartan daily with blood pressure ...

Swiss pharma giant Novartis has expressed its satisfaction at a decision by the US Court of Appeals for the Federal Circuit ...

However, they are also possible therapeutic agents due to their potentially beneficial physiological effects. The angiotensin receptor–neprilysin inhibitor, sacubitril/valsartan, simultaneously ...

The U.S. Court of Appeals for the Federal Circuit (CAFC) today issued a precedential decision reversing a district court’s ...

In another such trial (VALUE), researchers randomized 15,245 hypertensive patients (minimum age, 50; mean BP, 155/87 mm Hg) in 31 countries to receive the angiotensin-receptor blocker valsartan or ...

In our Case of the Week, the Federal Circuit revived Novartis’s US Patent No. 8,101,659 by reversing the district court’s decision which found the patent invalid for lack of written description. The ...

Sacubitril/valsartan significantly reduced cardiomyopathy risk by 77% in patients on anthracycline chemotherapy compared to placebo. The SARAH trial highlights the need to identify high-risk ...

Novartis, an innovative medicines company, announced that the company is pleased with the decision by the US Court of Appeals for the Federal Circuit (CAFC) that affirms the validity of the Entresto ...

In a pivotal decision Friday, the Federal Circuit revived a key patent for Novartis' blockbuster heart failure drug Entresto, ...

Cardiomyopathy is a form of cardiotoxicity that refers to heart damage caused by cancer treatments involving chemotherapy. The SARAH clinical trial examined the effects of the heart-failure medication ...

Several previous analytical methods have been reported for the determination of sacubitril and valsartan in rat plasma using liquid chromatography (LC) with fluorescence detector 10 and liquid ...

Novartis (NYSE:NVS) said the U.S. Court of Appeals for the Federal Circuit has upheld the company's U.S. combination patent for its blockbuster cardiac drug Entresto, also known as ...