Korean researchers uncover cerebellums role in pain regulation mechanisms Cerebellums newfound function in pain processing reshapes research perspectives ...

In addition to the N– and C–terminal regions, helices α1 and α3 contribute side chains ... and single or double site mutants of the EphA4 receptor SAM domain. Analytical centrifugation ...

Minipress (prazosin), a drug commonly used to treat high blood pressure and urinary retention, has been shown in some studies to be safe and effective in managing nightmares and sleep disturbances in ...

Shenzhen Key Laboratory of Systems Medicine for inflammatory diseases, School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, China; Department of Cardiovascular ...

The study identifies the adhesion G-protein-coupled receptor A3 (ADGRA3) as a potential target for activating adaptive thermogenesis in white and brown adipose tissue, providing valuable information ...

The tools that we use are biochemical properties like disease-relevant heteromultivalent ligand-receptor interactions, integrated with biophysical attributes ... Nanomedicine platform for targeting ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...

1 Cytokine Receptor Laboratory, Faculty of Medicine and Health Sciences, Department of Biochemistry, Ghent University, Ghent, Belgium 2 VIB Medical Biotechnology Center, VIB, Ghent, Belgium Under ...

Finally, over a certain level of mossy fiber background activity, the circuit generated coherent oscillations in the theta-frequency band. All these processes were fine-tuned by NMDA and GABA-A ...