20 devilish questions to test your knowledge of the Shipping Forecast. The Shipping Forecast Centenary A collection of programmes and features celebrating 100 years of the Shipping Forecast. 25 ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...