Sotorasib is under clinical development by Amgen and currently in Phase II for Solid Tumor. According to GlobalData, Phase II drugs for Solid Tumor have a 37% phase transition success rate (PTSR) ...
Department of Chemistry, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, Tamil Nadu, India ...
The drug is an antineoplastic agent that acts by blocking the activity of hypoxia-inducible factor 2 alpha (HIF-2α), which regulates cellular proliferation, angiogenesis, and tumor growth.