ATF6 is spliced into ATF6P50 by the Golgi apparatus to exert its biological activity. The three activated receptor proteins also start the transcription of UPR in the nucleus. The cell damage and ...

Epstein-Barr virus (EBV) infects more than 90% of the human population worldwide and establishes lifelong infection in hosts by switching between latent and lytic infection. EBV latency can be ...

Smaller fractions of the N-glycoproteome reside in the ER (5%), Golgi (4%), or lysosomes (2%). UGGT substrates are therefore significantly enriched for lysosomal proteins compared to the ...

The design principles dictating the spatio-temporal organisation of eukaryotic cells, and in particular the mechanisms controlling the self-organisation and dynamics of membrane-bound organelles such ...