Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell ...

Their study indicated that intermittent fasting selectively induced apoptosis—programmed cell death—in activated hair follicle stem cells (HFSCs). The results of a small clinical trial also ...

This study investigates the role of Caspar (Casp), an orthologue of human Fas-associated factor-1, in regulating the number of primordial germ cells that form during Drosophila embryogenesis. The ...

Dysregulation of caspase-8 is intricately linked to the complex biological underpinnings of HCC. In this manuscript, we provide a comprehensive review of the regulatory roles of caspase-8 in apoptosis ...

MPs represent only one type of vesicles released from cells. The other major vesicle types are exosomes and apoptotic bodies (Figure 1). In contrast to MPs, exosomes are derived from ...

As the Fas receptor–ligand pathway is involved in c-myc-induced apoptosis in fibroblasts 6 and MYCN overexpression sensitizes NB cells to apoptotic signals 2, one or more components of this ...

Department of Chemistry, University of California, Riverside, Riverside, CA, United States HeLa cells were cultured in DMEM supplemented with 10% FBS and 1% penicillin and streptomycin. Cells were ...