Both aspirin and ibuprofen inhibit COX-1 and COX-2, but acetaminophen appears to inhibit only COX-3. Very recently, additional anti-inflammatory agents have been introduced, ones that inhibit COX ...

Up to 20% of asthmatic patients demonstrate hypersensitivity to aspirin and NSAIDs ... of the arachidonic acid metabolites from the COX pathway toward the LO pathway, leading to an increased ...