Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...

中国农业科学院哈尔滨兽医研究所翁长江研究员团队2024年12月发表在Journal of Virology杂志上的一篇名为“Autophagy promotes p72 ... 粒子在2 hpi时与红色荧光LC3点部分共定位，但在感染后期，LC3和新合成的p72几乎没有共定位。 由于SQSTM1/ p62在自噬过程中起关键作用，对 ...

This study aimed to elucidate how PGD2 inhibits the stemness of gastric cancer stem cells (GCSCs) via autophagy and its underlying molecular mechanism to provide a theoretical basis for the treatment ...

While autophagy is relevant to many biological processes and often serves as a gatekeeper of homeostasis, when something goes wrong it can either lead to disease or be activated to fight against it.

1 School of Public Health, Shandong Second Medical University, Weifang, China 2 Experimental Center for Medical Research, Shandong Second Medical University, Weifang, China Introduction: Non-alcoholic ...

Although the mechanism by which ATG8ylation regulates the retromer remains unclear, the findings provide important insights with solid supporting evidence. ATG5 is one of the core autophagy proteins ...

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12月9日，哈尔滨医科大学与中国科学院研究人员合作共同在期刊《Advanced Science》上发表了题为“In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux ...