This study highlights the importance of proteins that are involved in the regulation of the actin cytoskeleton, revealing fundamental roles for HEM1 in both innate and adaptive immune cells.

When applied to breast cancer cell lines in vitro ... In addition, MicroQuin compounds act on the actin cytoskeleton to block the formation of F-actin in cancerous cells and inhibit their ...

and consequently defects in regulation of the actin cytoskeleton lead to various diseases including cancer progression, as well as neurological and immunological disorders. Our group uses a wide range ...

In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions ... identify new therapeutic targets, especially for cancer. To tackle these ...

We want to understand how these changes are co-ordinated by dynamic regulation of the actin cytoskeleton throughout cell division. We are particularly interested in how cells divide within epithelial ...

found that cancer cells adapt their migration based on the physical and biochemical properties of their surroundings. Cells stained with red for their actin skeleton and with blue for their ...

Their movement is enabled by the actin cytoskeleton, a network of proteins in cells which, similar to the human skeleton, provides structure and support. During embryonic development, Shh acts as ...