It's true that celecoxib doesn't block that enzyme as much as other NSAIDs, and some evidence suggests that it's less likely than those drugs to cause abdominal pain, indigestion, and nausea.

Celebrex (celecoxib) and ibuprofen are both classified as nonsteroidal anti-inflammatory drugs (NSAIDs). Both are commonly ...

[1] A case of this drug reaction from celecoxib is reported. A 61-year-old nonatopic woman presented with 15 round, red-brown, edematous, moderately itching patches. Their size varied from 2 to 10 ...